Projects supported by the Danish 3R-Center
3R-projects supported in 2024
3R-projects supported in 2023
3R-projects supported 2022
- Replacement of meningioma animal models with a meningioma ex vivo/organoid model to test pharmacological advances in meningioma treatment
- The PluriLum assay: A novel stem cell-based assay for testing of chemicals’ embryotoxic effects
- Use of ultrasound for early diagnosis of necrotizing enterocolitis in laboratory premature piglets
3R-projects supported 2021
3R-projects supported 2020
- Establishment of an in vitro model to investigate extracellular matrix and vascular mechanical interactions in human arterial disease
- Introduction of new human ex vivo model systems to study tumorigenesis in kidney cancer
- Fighting irreproducibility in preclinical medicine using a meta-analytical approach for detecting flaws in behavior-based testing
3R-projects supported 2019
3R-projects supported 2018
3R-projects supported 2017
- Use of Primary Isolates From Human Kidney to Study the Molecular Aspects of Blood Pressure Regulation
- Developing FACS based in vitro assays to measure antibody mediated protection against infection with intracellular bacteria
- Implementation of analgesic refinement in rats used as models for arthritis and inflammatory pain
3R-projects supported 2016
3R-projects supported in 2015
- An in vitro method to predict acute lung toxicity due to pulmonary surfactant inhibition
- A Refined Approach to Producing Polyclonal Antibodies in Chickens – Completely Replacing All Invasive Elements by Combining Immunizations with Routine Aerosol-based Vaccinations
- An alternative to animal experiments: Development of an in vitro human skin model for evaluation of topical antimicrobial compounds
3R-projects supported in 2014
- Refinement of animal models of pain: Establishment of strategies to alleviate avoidable pain in rat models for pain and inflammation
- Pathological and immunological consequences of basic experimental animal procedures in mice
- Reducing the group size in studies of dermatitis by standardization of the gut microbiota
- Establishment of an In vitro model for diabetic atherosclerosis
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